MLS Best Bets for April 22, 2026

Charlotte FC vs. Orlando City SC

Event: Wed, Apr 22 · 7:30 PM EDT

Odd$mith pick: Over 3.0 (-113)

Result: Win · Charlotte FC 1, Orlando City SC 4

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FC Cincinnati vs. New York City FC

Event: Wed, Apr 22 · 7:30 PM EDT

Odd$mith pick: New York City FC ML (-125)

Result: Loss · FC Cincinnati 4, New York City FC 4

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LA Galaxy vs. Columbus Crew SC

Event: Wed, Apr 22 · 7:30 PM EDT

Odd$mith pick: Columbus Crew SC ML (-125)

Result: Win · LA Galaxy 1, Columbus Crew SC 2

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New England Revolution vs. Atlanta United FC

Event: Wed, Apr 22 · 7:45 PM EDT

Odd$mith pick: Atlanta United FC ML (-110)

Result: Loss · New England Revolution 2, Atlanta United FC 1

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Colorado Rapids vs. Los Angeles FC

Event: Wed, Apr 22 · 10:30 PM EDT

Odd$mith pick: Los Angeles FC -1.5 (-108)

Result: Loss · Colorado Rapids 0, Los Angeles FC 0

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