MLS Best Bets for April 25, 2026

Atlanta United FC vs. Toronto FC

Event: Sat, Apr 25 · 1:00 PM EDT

Odd$mith pick: Toronto FC ML (-120)

Result: Loss · Atlanta United FC 2, Toronto FC 1

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New England Revolution vs. Inter Miami CF

Event: Sat, Apr 25 · 7:30 PM EDT

Odd$mith pick: Inter Miami CF -1.5 (-105)

Result: Loss · New England Revolution 1, Inter Miami CF 1

Featured analysis: Inter Miami's Dynasty Continues: Why They're the Clear Choice Over New England

Inter Miami's attacking firepower and New England's shaky defense make the Herons the obvious play at -255.

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New York Red Bulls vs. FC Cincinnati

Event: Sat, Apr 25 · 7:30 PM EDT

Odd$mith pick: Under 3.5 (-110)

Result: Win · New York Red Bulls 0, FC Cincinnati 2

Featured analysis: FC Cincinnati -125: The Steady Hand in a Jittery Matchup

FC Cincinnati's defensive consistency and shot volume edge justify the slight price over New York Red Bulls.

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Orlando City SC vs. D.C. United

Event: Sat, Apr 25 · 7:30 PM EDT

Odd$mith pick: D.C. United ML (-120)

Result: Win · Orlando City SC 2, D.C. United 3

Featured analysis: DC United ML -125: The Steady Hand in a Clash of Struggles

D.C. United's defensive structure and scoring consistency make them the logical play over a porous Orlando side.

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Philadelphia Union vs. Columbus Crew SC

Event: Sat, Apr 25 · 7:30 PM EDT

Odd$mith pick: Columbus Crew SC ML (-120)

Result: Win · Philadelphia Union 0, Columbus Crew SC 2

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Charlotte FC vs. Nashville SC

Event: Sat, Apr 25 · 8:30 PM EDT

Odd$mith pick: Under 2.5 (100)

Result: Loss · Charlotte FC 2, Nashville SC 4

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Houston Dynamo vs. Austin FC

Event: Sat, Apr 25 · 8:30 PM EDT

Odd$mith pick: Austin FC ML (125)

Result: Win · Houston Dynamo 0, Austin FC 2

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San Jose Earthquakes vs. St. Louis City SC

Event: Sat, Apr 25 · 8:30 PM EDT

Odd$mith pick: Over 3.0 (-110)

Result: Win · San Jose Earthquakes 3, St. Louis City SC 2

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Sporting Kansas City vs. Chicago Fire

Event: Sat, Apr 25 · 8:30 PM EDT

Odd$mith pick: Under 3.5 (-115)

Result: Loss · Sporting Kansas City 0, Chicago Fire 5

Featured analysis: Chicago Fire -380: A Calculated Play on Stability in a High-Stakes MLS Clash

Chicago Fire at -380 offers a compelling value as the more consistent and defensively sound team in a matchup where Sporting Kansas City’s recent volatility creates a clearer path for the Fire to capitalize.

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Colorado Rapids vs. Vancouver Whitecaps FC

Event: Sat, Apr 25 · 10:30 PM EDT

Odd$mith pick: Vancouver Whitecaps FC -1.5 (-115)

Result: Win · Colorado Rapids 1, Vancouver Whitecaps FC 3

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