MLB Best Bets for April 28, 2026

Official picks and featured analysis for this league on this event date.

Back to date view All event dates

Other leagues for this date

KBO NPB MLB NBA NHL

Tampa Bay Rays vs. Cleveland Guardians

Event: Tue, Apr 28 · 6:11 PM EDT

Odd$mith pick: Tampa Bay Rays ML (119)

Result: Win · Tampa Bay Rays 3, Cleveland Guardians 2

Open match page

Houston Astros vs. Baltimore Orioles

Event: Tue, Apr 28 · 6:36 PM EDT

Odd$mith pick: Over 9.0 (-110)

Result: Loss · Houston Astros 3, Baltimore Orioles 5

Open match page

San Francisco Giants vs. Philadelphia Phillies

Event: Tue, Apr 28 · 6:41 PM EDT

Odd$mith pick: Over 8.0 (-110)

Result: Loss · San Francisco Giants 0, Philadelphia Phillies 7

Open match page

St. Louis Cardinals vs. Pittsburgh Pirates

Event: Tue, Apr 28 · 6:41 PM EDT

Featured analysis: MLB Betting Preview: Cardinals vs. Pirates – Under 8.0 Runs (-102) is the Play

The Under 8.0 (-102) is the sharpest angle in this low-scoring Cardinals-Pirates matchup.

Read analysis

Boston Red Sox vs. Toronto Blue Jays

Event: Tue, Apr 28 · 7:08 PM EDT

Featured analysis: MLB Total Breakdown: Red Sox vs. Blue Jays

Under 7.5 is the strongest angle in this AL East matchup with shaky rotations and low-scoring trends.

Read analysis

Washington Nationals vs. New York Mets

Event: Tue, Apr 28 · 7:11 PM EDT

Odd$mith pick: New York Mets -1.5 (115)

Result: Win · Washington Nationals 0, New York Mets 8

Open match page

Los Angeles Angels vs. Chicago White Sox

Event: Tue, Apr 28 · 7:40 PM EDT

Featured analysis: MLB Over/Under Pick: Angels vs. White Sox – Over 8.0 Runs

Over 8.0 (-102) is the highest-conviction angle in this matchup.

Read analysis

Seattle Mariners vs. Minnesota Twins

Event: Tue, Apr 28 · 7:41 PM EDT

Odd$mith pick: Seattle Mariners ML (-125)

Result: Loss · Seattle Mariners 4, Minnesota Twins 11

Open match page

Chicago Cubs vs. San Diego Padres

Event: Tue, Apr 28 · 9:41 PM EDT

Featured analysis: MLB Total Over 8.5 in Padres-Cubs Series Opener

The Over 8.5 (-102) is the clearest path in a high-risk, high-reward Padres-Cubs matchup.

Read analysis

Odd$mith app

📱 Every pick, in your pocket. Daily best-bet cards, live odds, and the full board — free on Android. Get the app →