MLB Best Bets for August 22, 2026

New York Mets vs. Chicago White Sox

Event: Sat, Aug 22 · 7:10 PM EDT

Odd$mith pick: Chicago White Sox ML (-117)

Result: Loss · New York Mets 10, Chicago White Sox 5

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Athletics vs. Houston Astros

Event: Sat, Aug 22 · 7:11 PM EDT

Odd$mith pick: Over 8.0 (-110)

Result: Loss · Athletics 4, Houston Astros 3

Featured analysis: Athletics vs. Astros: Slugging Machine Meets Leaky Staff

Bet the over 8 runs as the A's firepower collides with an Astros rotation that’s been leaking like a busted hydrant.

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Chicago Cubs vs. Seattle Mariners

Event: Sat, Aug 22 · 7:16 PM EDT

Odd$mith pick: Seattle Mariners ML (-119)

Result: Win · Chicago Cubs 4, Seattle Mariners 5

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Pittsburgh Pirates vs. Los Angeles Dodgers

Event: Sat, Aug 22 · 7:16 PM EDT

Odd$mith pick: Pittsburgh Pirates +1.5 (-106)

Result: Win · Pittsburgh Pirates 3, Los Angeles Dodgers 4

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Cleveland Guardians vs. Colorado Rockies

Event: Sat, Aug 22 · 8:11 PM EDT

Odd$mith pick: Under 11.0 (-110)

Result: Win · Cleveland Guardians 4, Colorado Rockies 3

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