MLB Best Bets for September 16, 2026

Chicago White Sox vs. Cleveland Guardians

Event: Wed, Sep 16 · 1:11 PM EDT

Odd$mith pick: Over 8.0 (-110)

Result: Win · Chicago White Sox 3, Cleveland Guardians 6

Open match page

Detroit Tigers vs. Toronto Blue Jays

Event: Wed, Sep 16 · 3:08 PM EDT

Odd$mith pick: Toronto Blue Jays ML (-127)

Result: Win · Detroit Tigers 1, Toronto Blue Jays 5

Open match page

Los Angeles Dodgers vs. Cincinnati Reds

Event: Wed, Sep 16 · 6:41 PM EDT

Odd$mith pick: Cincinnati Reds +1.5 (102)

Result: Win · Los Angeles Dodgers 2, Cincinnati Reds 6

Open match page

Milwaukee Brewers vs. Pittsburgh Pirates

Event: Wed, Sep 16 · 6:41 PM EDT

Odd$mith pick: Pittsburgh Pirates ML (114)

Result: Loss · Milwaukee Brewers 5, Pittsburgh Pirates 4

Featured analysis: Pirates Moneyline Upset

Take the Pirates at +114 as Milwaukee’s busted fire‑hydrant staff hands them a clear path to victory.

Open match page Read analysis

San Diego Padres vs. Colorado Rockies

Event: Wed, Sep 16 · 8:41 PM EDT

Odd$mith pick: Under 11.5 (-114)

Result: Loss · San Diego Padres 9, Colorado Rockies 3

Open match page