NCAAF Best Bets for October 22, 2026

James Madison Dukes vs. Appalachian State Mountaineers

Event: Thu, Oct 22 · 7:00 PM EDT

Odd$mith pick: Over 56.5 (-110)

Result: Win · James Madison Dukes 31, Appalachian State Mountaineers 34

Featured analysis: Dukes vs. Mountaineers: The 56.5 Over is the Play

Two Sun Belt offenses are poised to turn a modest Tuesday night line into a comfortable cash.

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